DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss9

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	248	Identity:	92/248 - (37%)
Similarity:	130/248 - (52%)	Gaps:	15/248 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLD--GRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAG 92
            |.:|  .|||||......:.|.|.|::....|.||.|:.....::|||||.|. :..|.:....|
Mouse   749 PAMDKPTRIVGGISAVSGEVPWQASLKEGPRHFCGATVVGDRWLLSAAHCFNH-TKVEQVQAHLG 812

  Fly    93 SSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPV 157
            :.::....|...:|.:|.:.:||:|.....|:|.|:|.|.....||..:||:.|  ....|..||
Mouse   813 TVSLLGVGGSPVKLGLRRVALHPRYNPGILDFDVALLELAQPLVFNKYIQPVCL--PLAIHKFPV 875

  Fly   158 ----TVTGWGTTSEG-GTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDS 217
                .::|||...|| .|..|:||:.||.:::...|...|:..||.||||||...|..|:|||||
Mouse   876 GRKCMISGWGNMQEGNATKPDILQKASVGIIEQKMCGALYNFSLTDRMLCAGFLEGRVDSCQGDS 940

  Fly   218 GGPLVYNNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKES 265
            ||||....|     |.||||||.|||:.|.||||..:..:.||:::.::...|
Mouse   941 GGPLACEETPGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWILKAMSSDPS 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	87/229 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	88/232 (38%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473
		Tryp_SPc	756..984	CDD:214473	88/230 (38%)
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810