DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	84/233 - (36%)
Similarity:	124/233 - (53%)	Gaps:	17/233 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFP 99
            ::.||||....::|.|.|::....||||.|:..::.:|:||||....:.|::..:..|    :..
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFG----FLL 246

  Fly   100 TGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQ----PIELAKERPDHDTPVTVT 160
            :.||.:..|:.|:||..|....::.|.|::.|.....:.:.::    |....|..|:.|  |.||
  Rat   247 SKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSD--VVVT 309

  Fly   161 GWGTTSEGGTISDVLQEVSVNVVDNSNCKN--AYSIMLTSRMLCAGVNGGGKDACQGDSGGPLVY 223
            ||||....|...::||:..|.::||..|.:  ||..::|..|||||...|..||||||||||||.
  Rat   310 GWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVS 374

  Fly   224 NNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            .::     |.||||||..||....||||..|....||:
  Rat   375 EDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	82/230 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/232 (36%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	83/231 (36%)
		Tryp_SPc	187..415	CDD:238113	84/232 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920