DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lambdaTry and Tmprss4

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	230	Identity:	91/230 - (39%)
Similarity:	128/230 - (55%)	Gaps:	12/230 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFP 99
            |:|||.:.:...:|.|:|::|...|.|||:|...:.|::||||........:..:.|||:.:
  Rat   245 RVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAGSNKL--- 306

  Fly   100 TGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIEL--AKERPDHDTPVTVTGW 162
             |....|.|.:|.|.........:.|.|::.|.....|:.:|:||.|  :.|......||.|.||
  Rat   307 -GNSPSLPVAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIGW 370

  Fly   163 GTTSE-GGTISDVLQEVSVNVVDNSNC--KNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPLVYN 224
            |.|.| ||.:||.|.:.||.|:|::.|  ::||...:|:.|||||...||||.|||||||||:|:
  Rat   371 GFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGPLMYH 435

  Fly   225 N---TLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            .   .::||||||.||.....||||..|...|||:
  Rat   436 YDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	89/227 (39%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	90/229 (39%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346
		Tryp_SPc	245..470	CDD:214473	90/228 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80930
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910