DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and f9a

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_878288.2	Gene:	f9a / 359826	ZFINID:	ZDB-GENE-030714-2	Length:	503	Species:	Danio rerio

Alignment Length:	249	Identity:	86/249 - (34%)
Similarity:	127/249 - (51%)	Gaps:	21/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDG---RIVGGQDTNITQYPHQISMRYRGNHR--CGGTIYRSNQIISAAHCVNTLSGPEN--L 87
            |.:.|   ||:||......:.|.|:::..|...:  |||:|.....:|:||||   |.|..|  .
Zfish   245 PTVSGPKSRIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHC---LLGNHNGSF 306

  Fly    88 TIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNN--DYDAAILILDGDFEFNDAVQPIEL---- 146
            .|..|..::....|.:|.::|.::|.||:|.:..:  ::|.|:|.|.........|:||.|
Zfish   307 YIRVGEHDVSKIEGTEQNVDVIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTPTVRPICLGPMV 371

  Fly   147 -AKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGK 210
             :.......|..||:|||.....|..:..||::.:..||.:.||.:.|..:|..|.|||.:...|
Zfish   372 FSNTLLQSGTLATVSGWGRVRFQGRSAATLQKIELPYVDRTVCKESSSDPITHFMFCAGHSDSPK 436

  Fly   211 DACQGDSGGPLV--YNNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            ||||||||||.|  |:||  |.||:|||..||::...|||..|.:...|:..|:
Zfish   437 DACQGDSGGPHVMRYHNTWFLTGIISWGEECAKKGKYGVYTQVGNYYRWIQHTM 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	82/234 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	82/237 (35%)
f9a	NP_878288.2	GLA	19..83	CDD:214503
		EGF_CA	84..120	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	253..486	CDD:214473	82/235 (35%)
		Tryp_SPc	254..489	CDD:238113	82/237 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910