DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and flz

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	91/268 - (33%)
Similarity:	125/268 - (46%)	Gaps:	44/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NEEVHIPKLD---------GRIVGGQDTNITQYPHQISMR---YRG---NHRCGGTIYRSNQIIS 73
            |...|.|..:         ||||||:.:....||.|:.:|   :.|   .::|||.:..|..:|:
  Fly  1428 NLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVIT 1492

  Fly    74 AAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELE--------VREIIIHPKYRTLNNDYDAAILI 130
            ||||......  :|..|.|..:|      ..:||        |:.:|:|.:|.....:.|.|:|.
  Fly  1493 AAHCQPGFLA--SLVAVMGEFDI------SGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLE 1549

  Fly   131 LDGDFEFNDAVQPIELAKERPDH-DTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSI 194
            ||...:|:..:.||.:..:..|. ....||||||....||.:..|||||.|.:::||.|:..:..
  Fly  1550 LDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHT 1614

  Fly   195 ------MLTSRMLCAGVNGGGKDACQGDSGGPLVYNN-----TLLGIVSWGTGCAREKYPGVYCS 248
                  :||| .||||...|.||:|:||||||||...     .|.|.||.|..||....||||..
  Fly  1615 AGHNKKILTS-FLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMR 1678

  Fly   249 VPDVLDWL 256
            ......||
  Fly  1679 TTFYKPWL 1686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/245 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/247 (35%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	86/247 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910