DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and OVCH1

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	241	Identity:	88/241 - (36%)
Similarity:	131/241 - (54%)	Gaps:	20/241 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNI 96
            |..||.||::.....:|.|:.:|:.|:::|||.|.....|::|||||...:.|.:.||:||..:.
Human   606 LSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDR 670

  Fly    97 WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPV---- 157
            ......:|....:.||:|..:.||:.|.|.|::.|....|:|..|:|:.|    |....|:
Human   671 NLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCL----PHSAEPLFSSE 731

  Fly   158 --TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIM----LTSRMLCAGVNGGG-KDACQG 215
              .|||||:.|..|.::..||::.|:|::...|::.|...    :|.:|:|||....| ||.|||
Human   732 ICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQG 796

  Fly   216 DSGGPLVYNN-----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |||||||..:     .|.||||||.||.:...|||:..|...|||:
Human   797 DSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 842

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/235 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/237 (36%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	86/237 (36%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910