Protein Alignment lambdaTry and PRSS53

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 65/292 - (22%)
• Similarity: 106/292 - (36%)
• Gaps: 84/292 - (28%)

  Fly    33 DGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPE--NLTIVAGSSN 95
            :|..|.|      ::|.|.|:|.:|.|.|.|::.....:::||||....:..|  :.::|.||..
Human    40 EGNTVPG------EWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQ 98

  Fly    96 IWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQP---IELAKERPDHDTPV 157
            ....:...:|:.|..:.:...|...:...|.|:|.|         ..|   ..|...:|.|..|.
Human    99 REGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQL---------AHPTTHTPLCLPQPAHRFPF 154

  Fly   158 TVTGWGT-----TSEGG----------------TIS----------------------------D 173
            ..:.|.|     ||:|.                |:|                            .
Human   155 GASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPG 219

  Fly   174 VLQEVSVNVVDNSNCKNAYSIMLTSR---------MLCAGVNGGGKDACQGDSGGPLVY-----N 224
            .|:.:.:.::....|...|: .|..|         |||.|...|.:..||||||||::.     :
Human   220 TLRNLRLRLISRPTCNCIYN-QLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGH 283

  Fly   225 NTLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ....||:|:.:.||:|..|.:..:......||
Human   284 WVQAGIISFASSCAQEDAPVLLTNTAAHSSWL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	64/289 (22%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	64/290 (22%)
		Tryp_SPc	359..>512	CDD:473915