DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and prss60.3

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	264	Identity:	94/264 - (35%)
Similarity:	133/264 - (50%)	Gaps:	40/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LDGRIVGGQDTNITQYPHQISM---RYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGS 93
            |:.|||||.:.:...:|.|:|:   :| |.|.|||::..|..:::||||   |||....|:|
Zfish    32 LNTRIVGGVNASPGSWPWQVSLHSPKY-GGHFCGGSLISSEWVLTAAHC---LSGVSETTLV--- 89

  Fly    94 SNIWFPTGPQQELEVREI-------IIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERP 151
              ::.....||.:.:.|.       .:|..|.:..||.|.|:|.|.....|.:.::|:.||.:..
Zfish    90 --VYLGRRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNS 152

  Fly   152 DHD--TPVTVTGWGTTSEGGTI--SDVLQEVSVNVVDNSNCKNAY--SIMLTSRMLCAGVNGGGK 210
            .:.  |...:||||....|..:  ..:|||..:.||.|..| ||.  |..:|:.|:|||:..|||
Zfish   153 VYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC-NALLGSGTVTNNMICAGLTQGGK 216

  Fly   211 DACQGDSGGPLVYNNTLL-------GIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKESVGK 268
            |.||||||||:|   |.|       ||.|||.|||....||||..|.....|    ::.|.|:.|
Zfish   217 DTCQGDSGGPMV---TRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSW----ISSKISLNK 274

  Fly   269 IDFL 272
            ..|:
Zfish   275 PGFI 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	88/242 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	88/245 (36%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	88/249 (35%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900