DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and CLIPC1

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_552698.3	Gene:	CLIPC1 / 3291827	VectorBaseID:	AGAP008835	Length:	389	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	75/252 - (29%)
Similarity:	118/252 - (46%)	Gaps:	41/252 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IVGGQDTNITQYPHQI--------SMRYRGNHRCGGTIYRSNQIISAAHCV-NTLSGPENLTIV- 90
            ||.|:.....::||..        .:||    .|||::.....|::|.||: :|..||  .|||
Mosquito   143 IVDGELAKAREFPHMALIGFGEAPEIRY----LCGGSLVSDRFILTAGHCLTSTNFGP--ATIVR 201

  Fly    91 ------AGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKE 149
                  |.|::..||    ::.::.|.|.||:|:..::..|.|::.|:....|:...:||.|..:
Mosquito   202 LGELSLASSTDEAFP----EDYDIAERIPHPEYKQTSHYNDIALIKLNRKVIFSPYARPICLPLQ 262

  Fly   150 RPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY-------SIMLTSRMLCAGVNG 207
            ..........||||....|...|..|.:|::::.....||:.:       :.:..:..||||...
Mosquito   263 AAIPQKRAIATGWGAIGFGLEQSSALLKVTLDMFRFEECKDQFEPTRKLRTGLNATTQLCAGSRN 327

  Fly   208 GGKDACQGDSGGPL-VYNN-------TLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ..||.||||||||| |||:       |::|:.|:|..|.....|.||.:|...|.|:
Mosquito   328 STKDTCQGDSGGPLQVYNDANVYCTYTIIGVTSFGQNCGLAGVPAVYTTVYSYLSWI 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	74/249 (30%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	75/252 (30%)
CLIPC1	XP_552698.3	CLIP	39..79	CDD:197829
		Tryp_SPc	143..386	CDD:238113	75/252 (30%)
		Tryp_SPc	143..384	CDD:214473	74/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910