DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP011909

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_320620.4	Gene:	AgaP_AGAP011909 / 3291449	VectorBaseID:	AGAP011909	Length:	400	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	73/257 - (28%)
Similarity:	110/257 - (42%)	Gaps:	45/257 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHR-----CGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSS 94
            :||||::|.:.::|...:: ..|:..     ||.||..:...::||||....| ..||.::.|..
Mosquito   154 KIVGGEETLVNEFPMMAAL-VDGSKSGEGIFCGATIITNYHAVTAAHCYMGRS-IANLALLVGEH 216

  Fly    95 NIWFPTGPQQE----LEVREIIIHPKY--RTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDH 153
            :|  .||.:..    |.:..|.||..|  .|.::..|.||:....:..||..|.|..|
Mosquito   217 DI--TTGSESPYTALLLLASIKIHEGYSSTTSSSSNDIAIVRTRTEILFNAGVGPACL------- 272

  Fly   154 DTPV------------TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVN 206
              |:            ...||||...|...|:|..:|::.||:.|.|...|......:.||...
Mosquito   273 --PIKFVGASFVGIQLEAVGWGTLDYGAPKSNVPMKVALPVVNPSQCSALYPTFSAQQQLCTLT- 334

  Fly   207 GGGKDACQGDSGGPLVYNNT------LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVAD 262
             ..||.||.||||||.|.:.      |||.:.:|..||.:: |.|..:|.....|::....:
Mosquito   335 -PNKDTCQSDSGGPLFYTDAYNKRAYLLGTIGYGIACATDR-PSVSTNVLYYTQWIMNNTPE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	72/248 (29%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	73/251 (29%)
AgaP_AGAP011909	XP_320620.4	CUB	52..123	CDD:294042
		Tryp_SPc	154..388	CDD:214473	72/249 (29%)
		Tryp_SPc	155..391	CDD:238113	73/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910