DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lambdaTry and Ovch2

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_003749007.2	Gene:	Ovch2 / 308919	RGDID:	1564636	Length:	579	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	107/317 - (33%)
Similarity:	157/317 - (49%)	Gaps:	58/317 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFLVLGVGC-------------------SLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQIS 52
            :.|:||:.|                   ||..|..:|    ...|..|||||.......||.|:|
  Rat     8 LILILGIVCLEQGHSATLSSIRAPDCGKSLVKPWPQN----YFSLFSRIVGGSQVEKGSYPWQVS 68

  Fly    53 MRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKY 117
            ::.:..|.|||||..|..:|:||||:...:....|.:.||..::......:|.|.:..|||||::
  Rat    69 LKQKQKHICGGTIISSQWVITAAHCMANRNIALTLNVTAGEHDLSQAEPGEQTLAIETIIIHPQF 133

  Fly   118 RTLN-NDYDAAILILDGDFEFNDAVQPIELAK--ERPDHDTPVTVTGWGTTSEGGTISDVLQEVS 179
            .|.. .:||.|:|.:.|.|:|...|:|:.|.:  |:.:.....|..|||..||||::..|||:|:
  Rat   134 STKKPMNYDIALLKMVGTFQFGQFVRPVCLPEPGEQFNAGYICTTAGWGRLSEGGSLPQVLQQVN 198

  Fly   180 VNVVDNSNCKNAYSIMLTSR-------MLCAGVNGGGKDACQGDSGGPLVYNN-----TLLGIVS 232
            :.::.:..|:   ::|||.|       .||.|...||:|||||||||.|:..|     ||.|:.|
  Rat   199 LPILTHEECE---AVMLTLRNPITGKTFLCTGSPDGGRDACQGDSGGSLMCQNRKGAWTLAGVTS 260

  Fly   233 WGTGC-------AREK---YPGVYCSVPDVLDWLVETV-------ADKESVGKIDFL 272
            ||.||       ||:|   .||::..:..||.|:.|.|       :.|.|..::|.|
  Rat   261 WGLGCGRSWRNNARKKEQGSPGIFTDLRRVLPWIHEHVQTGHRRKSTKASCSELDGL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	91/244 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	91/247 (37%)
Ovch2	XP_003749007.2	Tryp_SPc	52..297	CDD:238113	91/247 (37%)
		CUB	317..420	CDD:238001	1/1 (100%)
		CUB	431..541	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810