DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	87/235 - (37%)
Similarity:	123/235 - (52%)	Gaps:	21/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFP 99
            |||||......::|.|.|:::.|:||||.|:..:..::|||||..|...|...|...|::    .
  Rat   212 RIVGGTSAEEGEWPWQSSLQWDGSHRCGATLISNTWLVSAAHCFRTHKDPSRWTASFGAT----L 272

  Fly   100 TGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPD--HD----TPVT 158
            ..|:....:|.||:|.||...::|||.|::.|.......:||..:.|    ||  |:    ..:.
  Rat   273 QPPKLTTGIRRIIVHEKYNYPSHDYDIALVELSRPVPCTNAVHKVCL----PDANHEFQPGQRMF 333

  Fly   159 VTGWGTTSEGGTISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCAGVNGGGKDACQGDSGGPL 221
            |||:|.....|...:.|::|.|:.:|...|.  .:|:..:|.||||||...|.||||||||||||
  Rat   334 VTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPL 398

  Fly   222 VYNNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |..:.     |.|:||||..|.:...||||..|....||:
  Rat   399 VTPDVRDVWYLAGVVSWGDECGQPNKPGVYTRVTAFRDWI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/232 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/234 (37%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	86/234 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910