DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Hpn

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_038958880.1	Gene:	Hpn / 29135	RGDID:	61982	Length:	559	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	95/259 - (36%)
Similarity:	134/259 - (51%)	Gaps:	33/259 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIV------AGS 93
            |||||||:::.::|.|:|:||.|.|.|||::...:.:::||||.     ||...::      ||:
  Rat   203 RIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCF-----PERNRVLSRWRVFAGA 262

  Fly    94 SNIWFPTGPQQELEVREIIIHPKYRTL------NNDYDAAILILDGDFEFNDAVQPIEL-AKERP 151
            .....|...|  |.|:.:|.|..|...      .|..|.|::.|.......:.:||:.| |..:.
  Rat   263 VARTSPHAVQ--LGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQA 325

  Fly   152 DHDTPV-TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDAC 213
            ..|..| ||||||.|...|..:.||||..|.::.|..|.:.  |...:..:|.|||...||.|||
  Rat   326 LVDGKVCTVTGWGNTQFYGQQAVVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDAC 390

  Fly   214 QGDSGGPLVYNN--------TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV--ADKESVG 267
            |||||||.|..:        .|.||||||||||..:.||||..|.|..:|:.:.:  :..|::|
  Rat   391 QGDSGGPFVCEDRISGTSRWRLCGIVSWGTGCALARKPGVYTKVIDFREWIFQAIKASGDETLG 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	92/243 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	92/246 (37%)
Hpn	XP_038958880.1	Hepsin-SRCR	92..200	CDD:401275
Hpn	XP_038958880.1	Tryp_SPc	204..441	CDD:238113	91/243 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910