DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and F11

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_006253206.1	Gene:	F11 / 290757	RGDID:	1309364	Length:	622	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	84/248 - (33%)
Similarity:	131/248 - (52%)	Gaps:	21/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTI 89
            :.|...|:..|:.||..:...::|.|:::.....|.|||:|..:..|::||||.:....|:.|.:
  Rat   377 DNVCTTKIRPRVFGGAASVHGEWPWQVTLHTTQGHLCGGSIIGNRWILTAAHCFSGTETPKTLRV 441

  Fly    90 VAGSSNIWFPTGPQQEL-------EVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELA 147
            ..|..|       |.|:       .|:|:|||.:|.:..:.:|.|:|.|:....:.|..:||.|.
  Rat   442 YGGIVN-------QSEINEDTTFFRVQEMIIHDQYTSAESGFDIALLKLEPAMNYTDFQRPICLP 499

  Fly   148 K--ERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY-SIMLTSRMLCAGVNGGG 209
            .  :|....|...|||||.|.....:...||:..|.:|.|..|:..| ...:|::::|||...||
  Rat   500 SKGDRNVVHTECWVTGWGYTKSRDEVQSTLQKAKVPLVSNEECQTRYRKHKITNKVICAGYKEGG 564

  Fly   210 KDACQGDSGGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            ||.|:|||||||...:.    |:||.|||.||.:::.||||.:|...:||::|
  Rat   565 KDTCKGDSGGPLSCKHNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILE 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	79/233 (34%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	81/237 (34%)
F11	XP_006253206.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..374	CDD:128519
		Tryp_SPc	387..615	CDD:214473	80/234 (34%)
		Tryp_SPc	388..615	CDD:238113	79/233 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810