DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss5

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_695223.2	Gene:	Tmprss5 / 266681	RGDID:	628625	Length:	445	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	96/240 - (40%)
Similarity:	128/240 - (53%)	Gaps:	12/240 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNT--LSGPENLTIVAGSS 94
            |..||||||.....::|.|.|:.....|.||.::.....:::||||:.:  ||...:..:.||..
  Rat   204 LASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRVHAGLV 268

  Fly    95 NIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIEL-AKERP-DHDTPV 157
            : .......|...|.:||.||.|...|:|||.|:|.|.....|:|.|..:.| |||:. ...:..
  Rat   269 S-HSAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQHFPQGSQC 332

  Fly   158 TVTGWGTTSEGGT-ISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDACQGDSGG 219
            .|:|||.|....| .||.||:..|.::....|.::  ||..||.||||||...|..|||||||||
  Rat   333 WVSGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGG 397

  Fly   220 PLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            |||..:    .|:|:||||.|||....||||..|.:.|||:.:||
  Rat   398 PLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTV 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	91/230 (40%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	92/233 (39%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:406055
Tmprss5	NP_695223.2	Tryp_SPc	208..441	CDD:238113	92/233 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910