DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Pamr1

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_776110.3	Gene:	Pamr1 / 210622	MGIID:	2445082	Length:	720	Species:	Mus musculus

Alignment Length:	288	Identity:	74/288 - (25%)
Similarity:	110/288 - (38%)	Gaps:	78/288 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EEVHIPKLDGRIVGGQDTNITQYPHQISMRYR--------GNHR------CGGTIYRSNQIISAA 75
            |....||..|          |::|.|.:: ||        |.|:      |.|.:.....::.||
Mouse   450 ESTPSPKTQG----------TRWPWQAAI-YRRTSGVHDGGLHKGAWFLVCSGALVNERTVVVAA 503

  Fly    76 HCVN-----TLSGPENLTIVAG---------SSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDA 126
            |||.     |:....:|.:|.|         ..:|       |.|.|..||:||.|..:..|.|.
Mouse   504 HCVTELGKATIIKTADLKVVLGKFYRDDDRDEKSI-------QNLRVSAIILHPNYDPILLDTDI 561

  Fly   127 AILILDGDFEFNDAVQPIELAKER----PDHDTPVTVTGWGTTSE---GGTISDVLQEVSVNVVD 184
            |:|.|......:..||||.||..|    ...::.:||.||...::   .|..:|.|....|.|||
Mouse   562 AVLKLLDKARISTRVQPICLATTRDLSTSFQESHITVAGWNILADVRSPGFKNDTLHYGMVRVVD 626

  Fly   185 NSNCKNAYS-----IMLTSRMLCAGVN-GGGKDACQGDSGGPLVYNNT----------LLGIVSW 233
            ...|:..:.     :.:|..|.||..: ....|.|..::||....:..          |:|:|||
Mouse   627 PMLCEEQHEDHGIPVSVTDNMFCASKDPSTPSDICTAETGGIAALSFPGRASPEPRWHLVGLVSW 691

  Fly   234 G--TGCAREKYPGVYCSVPDVL---DWL 256
            .  ..|:.    |:..:...||   ||:
Mouse   692 SYDKTCSN----GLSTAFTKVLPFKDWI 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	68/275 (25%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	70/277 (25%)
Pamr1	NP_776110.3	CUB	128..234	CDD:238001
		EGF_CA	240..272	CDD:238011
		CCP	280..342	CDD:153056
		CCP	<408..443	CDD:153056
		Tryp_SPc	461..718	CDD:238113	69/267 (26%)
		Tryp_SPc	461..715	CDD:214473	68/265 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910