DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss15

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_032967.1	Gene:	Tmprss15 / 19146	MGIID:	1197523	Length:	1069	Species:	Mus musculus

Alignment Length:	248	Identity:	86/248 - (34%)
Similarity:	128/248 - (51%)	Gaps:	30/248 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KLDGRIVGGQDTNITQYPHQISMRYRGNHR----CGGTIYRSNQIISAAHCVNTLS-GPENLTIV 90
            |:..:||||.|.....:|..:::.:|....    ||.::..|:.::||||||...: .|...|.|
Mouse   825 KVSPKIVGGSDAQAGAWPWVVALYHRDRSTDRLLCGASLVSSDWLVSAAHCVYRRNLDPTRWTAV 889

  Fly    91 AG---SSNIWFPTGPQ-QELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKER- 150
            .|   .||:   |.|| ....|.:|:|:|.|.......|.|::.|:....:.|.:|||.|.:|.
Mouse   890 LGLHMQSNL---TSPQVVRRVVDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICLPEENQ 951

  Fly   151 ---PDHDTPVTVTGWG--TTSEGGTISDVLQEVSVNVVDNSNCKN---AYSIMLTSRMLCAGVNG 207
               |..  ..::.|||  ..:.|.|: |||:|..|.::.|..|:.   .|:|  |..|:|||...
Mouse   952 IFIPGR--TCSIAGWGYDKINAGSTV-DVLKEADVPLISNEKCQQQLPEYNI--TESMICAGYEE 1011

  Fly   208 GGKDACQGDSGGPLV--YNNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ||.|:|||||||||:  .||.  |:|:.|:|..||...:||||..|...::|:
Mouse  1012 GGIDSCQGDSGGPLMCQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWI 1064

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	84/241 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/243 (35%)
Tmprss15	NP_032967.1	SEA	53..154	CDD:214554
		LDLa	228..261	CDD:197566
		CUB	270..376	CDD:294042
		MAM	392..549	CDD:279023
		MAM	392..547	CDD:99706
		CUB	569..676	CDD:278839
		LDLa	688..722	CDD:238060
		SR	723..816	CDD:214555
		SRCR	728..819	CDD:278931
		Tryp_SPc	829..1064	CDD:214473	84/242 (35%)
		Tryp_SPc	830..1066	CDD:238113	85/243 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810