DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Klkb1

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_032481.2	Gene:	Klkb1 / 16621	MGIID:	102849	Length:	638	Species:	Mus musculus

Alignment Length:	239	Identity:	86/239 - (35%)
Similarity:	139/239 - (58%)	Gaps:	12/239 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KLDGRIVGGQDTNITQYPHQISMRYR---GNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAG 92
            |::.|||||.:.::.::|.|:|::.:   ..|.|||:|.....:::||||.:.:..|:...|..|
Mouse   386 KINARIVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 450

  Fly    93 SSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPV 157
            ..::...|.......::|:|||.:|:....:||.|::.|.....:.:..:||.| ..:.|.:|..
Mouse   451 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPICL-PSKADTNTIY 514

  Fly   158 T---VTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY-SIMLTSRMLCAGVNGGGKDACQGDSG 218
            |   |||||.|.|.|...::||:.::.:|.|..|:..| ..::..:|:|||...||.|||:||||
Mouse   515 TNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSG 579

  Fly   219 GPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            ||||..::    |:||.|||.||||:..||||..|.:.:||::|
Mouse   580 GPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILE 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	82/230 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/234 (36%)
Klkb1	NP_032481.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	83/231 (36%)
		Tryp_SPc	391..621	CDD:238113	82/230 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810