DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and Tmprss2

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	91/242 - (37%)
Similarity:	130/242 - (53%)	Gaps:	28/242 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV-NTLSGPENLTIVAG--SSNI 96
            |||||...:...:|.|:|:..:|.|.|||:|.....|::||||| ..||.|...|..||  ..::
  Rat   253 RIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSL 317

  Fly    97 WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPI---------ELAKERPD 152
            .| .|.:.::|  ::|.||.|.:...:.|.|::.|.....|||.|:|:         :||:|
  Rat   318 MF-YGSRHQVE--KVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDLAQE--- 376

  Fly   153 HDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNC--KNAYSIMLTSRMLCAGVNGGGKDACQG 215
                ..::|||.|.|.|..||||....|.:::.|.|  |..|:.::|..|:|||...|..|:|||
  Rat   377 ----CWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQG 437

  Fly   216 DSGGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            |||||||....    |:|..|||:|||:...||||.:|....||:.:
  Rat   438 DSGGPLVTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQ 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	89/237 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	90/241 (37%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133
		Tryp_SPc	253..482	CDD:214473	90/238 (38%)
		Tryp_SPc	254..485	CDD:238113	90/241 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810