DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP001246

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_321901.4	Gene:	AgaP_AGAP001246 / 1281921	VectorBaseID:	AGAP001246	Length:	283	Species:	Anopheles gambiae

Alignment Length:	266	Identity:	79/266 - (29%)
Similarity:	127/266 - (47%)	Gaps:	32/266 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ILVVFLVLGVGCSLADPIYRNEEVHI---------PKLDGRIVGGQDTNITQ-YPHQISMRYRGN 58
            :|:...|.||..:.|...:.:.:..:         .|..||||||  |.:|: .|:.:|:|..|.
Mosquito    15 VLLALCVAGVWSNEAQDAWASRQRRVQATPNGDGQKKFSGRIVGG--TELTEPLPYLLSLRDSGF 77

  Fly    59 HRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAG-------SSNIWFPTGPQQELEVREIIIHPK 116
            |.||.:|..:...:|||||.:..|....||::||       ::.|.|        :|..:..||.
Mosquito    78 HICGASIINAKHALSAAHCQSPPSDVNRLTLLAGITKRTDETNGILF--------KVANVTTHPD 134

  Fly   117 YRTLNNDYDAAILILDGDF--EFNDAVQPIELAKERPDHDTPVTVTGWGTTSEGGTISDVLQEVS 179
            :.......|.||:.:...|  ..|.|..|:.....:....:..:|:|||.|::...::..|:.|.
Mosquito   135 FSLKTYLSDVAIIRIVTSFLDHPNLAAIPLISTTYKLRVSSVASVSGWGLTAQDSMLAPTLRTVR 199

  Fly   180 VNVVDNSNCKNAY-SIMLTSRMLCAGVNGGGKDACQGDSGGPLVYNNTLLGIVSWGTGCAREKYP 243
            :.:|..|:|.|.: .:.:....:|||  ..|:|:|.||||||||.:...:|:||||.......||
Mosquito   200 IPIVSYSSCVNKWRPVPIVWTAICAG--HPGRDSCNGDSGGPLVQDGVQIGLVSWGADRCGSDYP 262

  Fly   244 GVYCSV 249
            |:|..|
Mosquito   263 GIYTYV 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	72/226 (32%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	71/225 (32%)
AgaP_AGAP001246	XP_321901.4	Tryp_SPc	55..270	CDD:214473	72/226 (32%)
AgaP_AGAP001246	XP_321901.4	Tryp_SPc	56..270	CDD:238113	71/225 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D109274at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830