DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP001366

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_321777.4	Gene:	AgaP_AGAP001366 / 1281814	VectorBaseID:	AGAP001366	Length:	563	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	72/258 - (27%)
Similarity:	117/258 - (45%)	Gaps:	36/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IPKLDGRIVGGQDTNITQYPHQISMRYRG-----NHRCGGTIYRSNQIISAAHCVNTLSGPENLT 88
            :||.:..:..|..:...|:|...:: ||.     .:.||.|:......|:||||| ||. ..:..
Mosquito   308 VPKANPLVTHGTVSERGQFPWHGAL-YRSTVTELKYLCGATLISRRASITAAHCV-TLE-KSSKP 369

  Fly    89 IVAGSSNIWFP-------TGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIEL 146
            :.|||..::|.       .||:::.::|.|.|..:|:......|.|:|:|..|.::::.|:|:.|
Mosquito   370 VDAGSLLLYFGKIDLSKWNGPEEDAQIRSIHIPAQYQHERFFNDIAVLVLKEDIKYSNFVRPVCL 434

  Fly   147 AKERPDHDTPVT----VTGWGTTSEGGTISDVLQEVSVNVVDNSNC----KNAYSIMLTSRMLCA 203
            .....|:.|.:.    |.||| .:|.|.:|..|....:.||.:..|    ::.:|.:.:....||
Mosquito   435 WNFDDDYKTLINKIGFVPGWG-YNEHGLVSSRLSFAQMPVVAHETCIWSNRDFFSKVTSDTSFCA 498

  Fly   204 GVNGGGKDACQGDSGGPLVY--NNT--LLGIVSWGTG------CAREKYPGVYCSVPDVLDWL 256
            |.. .|...|.|||||.:|:  ||.  |.||||....      |..:.|. |:........|:
Mosquito   499 GFK-NGTSVCNGDSGGGMVFKHNNLWYLRGIVSVSAALQDRFHCDSKHYV-VFTDAAKFTSWI 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	69/249 (28%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	70/251 (28%)
AgaP_AGAP001366	XP_321777.4	GD_N	15..124	CDD:292649
		Tryp_SPc	315..560	CDD:238113	70/251 (28%)
		Tryp_SPc	315..559	CDD:214473	69/249 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910