DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP011908

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_320621.4	Gene:	AgaP_AGAP011908 / 1280755	VectorBaseID:	AGAP011908	Length:	391	Species:	Anopheles gambiae

Alignment Length:	235	Identity:	69/235 - (29%)
Similarity:	111/235 - (47%)	Gaps:	21/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISM--RYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIW 97
            :||||....:.:|...:.:  ....|..|.|.|..|..:::||||..|:.....:..:.|..:
Mosquito   153 KIVGGSVAGVNEYTAMVGLLDPLTVNVFCSGAIISSRYVLTAAHCARTIPSVSRVQALVGDHD-- 215

  Fly    98 FPTG---PQQEL-EVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHD---T 155
            :.:|   |...: .:.:||.|..|.....:.|.|:|....:.:||..|.||.|......:.   .
Mosquito   216 YRSGLDTPYSAIYNIEQIISHEYYNEQTRNNDIALLKTSTEMDFNRGVGPICLPFTYSTYSFGGL 280

  Fly   156 PVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDSGGP 220
            .|.:.||||||.||.:|.:|::.::||:.|:||...|   :..:.:|  ....|:|:||.||||.
Mosquito   281 SVDIAGWGTTSFGGPMSTILRKTTLNVLQNANCTAPY---VNDQKIC--TFAVGRDSCQYDSGGA 340

  Fly   221 LVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |....:    .:||:|:|:.||... |.|...|...|.|:
Mosquito   341 LFLRGSQRMYSIGIISYGSACAAST-PSVATRVTAYLSWI 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	68/232 (29%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	69/234 (29%)
AgaP_AGAP011908	XP_320621.4	CUB	26..>106	CDD:294042
		Tryp_SPc	153..379	CDD:214473	68/233 (29%)
		Tryp_SPc	154..382	CDD:238113	69/234 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910