DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP011912

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_320615.4	Gene:	AgaP_AGAP011912 / 1280750	VectorBaseID:	AGAP011912	Length:	408	Species:	Anopheles gambiae

Alignment Length:	237	Identity:	72/237 - (30%)
Similarity:	111/237 - (46%)	Gaps:	24/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHR--CGGTIYRSNQIISAAHCVN----TLSGPENLTIVAGS 93
            :||.|..|.:.::|....:....:..  ||.||......|:||||:.    :.||     ::.|.
Mosquito   169 KIVNGVPTLVNEFPMMAGLVDSSSRSVFCGATIISDYHSITAAHCMRGRSLSASG-----LLVGD 228

  Fly    94 SNIWFPTGPQQELEVR--EIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHD-- 154
            .|:...|.....:.:|  .|..||:|....:..|.|::.......||.||.|..|.......:
Mosquito   229 HNLSVGTDTSYSVLMRLASITNHPQYVVSPSRNDIALVRTADRIAFNAAVGPACLPFRYSTSNFA 293

  Fly   155 -TPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDSG 218
             :.|..|||||...|...|:||::||:||:...:|:::...:|.|. :|...  .|||.||.|||
Mosquito   294 GSIVEATGWGTMDFGAPTSNVLRKVSLNVISEQSCQSSMPNILASH-ICTYT--PGKDTCQYDSG 355

  Fly   219 GPLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |||::..    .|:|:|::|..||..| |.|...:...|.|:
Mosquito   356 GPLLFTTGGRVYLVGVVNYGVSCASSK-PSVSSRITSYLSWI 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	71/234 (30%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	72/236 (31%)
AgaP_AGAP011912	XP_320615.4	CUB	55..155	CDD:238001
		Tryp_SPc	169..396	CDD:214473	71/235 (30%)
		Tryp_SPc	170..399	CDD:238113	72/236 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910