DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP009966

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_319102.4	Gene:	AgaP_AGAP009966 / 1279386	VectorBaseID:	AGAP009966	Length:	288	Species:	Anopheles gambiae

Alignment Length:	269	Identity:	106/269 - (39%)
Similarity:	149/269 - (55%)	Gaps:	26/269 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ILVVFLVLG-VGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYR 67
            :||.|.::. ||||      |:.|.:......|||||...:|..||:|:|:| ||.|.||.:|..
Mosquito    19 VLVSFTIVSVVGCS------RSAENYDHTNGERIVGGVPVDIRDYPYQVSLR-RGRHFCGESIID 76

  Fly    68 SNQIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILD 132
            |..|::||||..|::. .||.|..|||::   ....:.:.||.|:.|||..:. :|||.::|.||
Mosquito    77 SQWILTAAHCTRTINA-RNLWIHVGSSHV---NDGGESVRVRRILHHPKQNSW-SDYDFSLLHLD 136

  Fly   133 GDFEFNDAVQPIELAKERPDHDTPV---------TVTGWGTTSEGGTISDVLQEVSVNVVDNSNC 188
            .....:::||||.|.|  |....|.         .|:|||.|......:.||:..:|.:.::..|
Mosquito   137 QPLNLSESVQPIPLRK--PSASEPTGELSDGTLCKVSGWGNTHNPDESALVLRAATVPLTNHQQC 199

  Fly   189 KNAYSIM--LTSRMLCAGVNGGGKDACQGDSGGPLVYNNTLLGIVSWGTGCAREKYPGVYCSVPD 251
            ...|..:  :|..|:|||.:.||||:||||||||||.:..|.|:||||.|||...|||||..|..
Mosquito   200 SEVYEGIGSVTESMICAGYDEGGKDSCQGDSGGPLVCDGQLTGVVSWGKGCAEPGYPGVYAKVST 264

  Fly   252 VLDWLVETV 260
            ..:|:.:||
Mosquito   265 AYEWIEQTV 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	94/230 (41%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	94/233 (40%)
AgaP_AGAP009966	XP_319102.4	Tryp_SPc	45..269	CDD:214473	94/231 (41%)
AgaP_AGAP009966	XP_319102.4	Tryp_SPc	46..272	CDD:238113	94/233 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D109274at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830