DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP008403

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_317049.4	Gene:	AgaP_AGAP008403 / 1277577	VectorBaseID:	AGAP008403	Length:	873	Species:	Anopheles gambiae

Alignment Length:	260	Identity:	73/260 - (28%)
Similarity:	125/260 - (48%)	Gaps:	39/260 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GQDTNITQYPHQISMRYRGNH-----RCGGTIYRSNQIISAAHCV--NTLSGPENLTIVAGSSNI 96
            |:...:.::.|..::.:.|.:     .|||::...|.:::||||.  :..:.|:  .:..|..|:
Mosquito    20 GRPAYLREFAHMAAVGWTGENGKIDWNCGGSLIWENYVLTAAHCTADDNNAAPD--VVRLGDINL 82

  Fly    97 WFPTGPQ--QELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTP--- 156
            ...:..:  |:|::.|||.||::|..:..:|.|:|.|:.:...:|.|.|..|..   |.:.|
Mosquito    83 DDDSDDKYAQQLKIVEIIRHPEHRFSSRYHDLALLRLERNVTLHDTVAPGCLWN---DEEIPFPS 144

  Fly   157 VTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY-------SIMLTSRMLCAGVNGGGKDACQ 214
            :..||||:|  |...:.:|.:||:::|..|.|...|       ...|....||||  ....|.|.
Mosquito   145 MEATGWGST--GFAKTPILLKVSLSLVPKSTCDQQYRKGDRGLRQGLQDYQLCAG--DIKMDTCP 205

  Fly   215 GDSGGPL---VYNNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKESV--GKI 269
            |||||||   :..|.     ::.:.|:|:.|. :..||||..|...:.|:...:|.:..:  |||
Mosquito   206 GDSGGPLQMKLLANAKMTPFIIAVTSFGSVCG-QSTPGVYMKVSPYIPWIRSELAKRGELIRGKI 269

Fly 270 269
Mosquito 270 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	68/242 (28%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	69/246 (28%)
AgaP_AGAP008403	XP_317049.4	Tryp_SPc	20..256	CDD:238113	69/245 (28%)
		Tryp_SPc	20..254	CDD:214473	68/243 (28%)
		Tryp_SPc	324..552	CDD:304450
		CLIP	577..617	CDD:295450
		Tryp_SPc	656..872	CDD:304450
		Tryp_SPc	656..869	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910