DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP005664

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_315684.2	Gene:	AgaP_AGAP005664 / 1276347	VectorBaseID:	AGAP005664	Length:	306	Species:	Anopheles gambiae

Alignment Length:	245	Identity:	77/245 - (31%)
Similarity:	124/245 - (50%)	Gaps:	31/245 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYR---GNHRCGGTIYRSNQIISAAHCVNTLSGPENLTI----VAG 92
            |:|.||:....|:|:||::...   |...|||::..:|.:::|||||  :.|...:.:    :.|
Mosquito    60 RVVNGQEATPGQFPYQIALLSNFLIGTGLCGGSVLTNNYVLTAAHCV--IMGTSTVALGGNAIMG 122

  Fly    93 SSNIWFPTGPQQELEVRE--IIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDT 155
            :.|...|...||.:....  |..||.|.:.|...|.|::.|:....|.|.:||..|...   .||
Mosquito   123 AHNRDAPEPSQQIIAFTSAGISAHPGYSSANIRNDIAVVRLNSPITFTDRIQPARLPAR---SDT 184

  Fly   156 ------PVTVTGWGTTSEGG-TISDVLQEVSVNVVDNSNCKNAY-SIMLTSRMLCAGVNG-GGKD 211
                  ..||:|:|.||:.. ..|.|:...|..|:.|::|...: ::::..:.:|  ::| ||:.
Mosquito   185 RQFGGFTGTVSGFGRTSDASQATSSVVMFTSNPVMTNADCIAQWNAVLIEPQNVC--MSGEGGRS 247

  Fly   212 ACQGDSGGPLVY---NNTLLGIVSWGT--GCAREKYPGVYCSVPDVLDWL 256
            ||.|||||||..   .:..:|:||:|:  ||| ...|.||..|...||::
Mosquito   248 ACNGDSGGPLAVQDGGSLQVGVVSFGSAAGCA-IGMPSVYARVSFFLDFI 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	76/242 (31%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	76/244 (31%)
AgaP_AGAP005664	XP_315684.2	Tryp_SPc	60..296	CDD:214473	77/243 (32%)
AgaP_AGAP005664	XP_315684.2	Tryp_SPc	61..299	CDD:238113	76/244 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920