DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP004858

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_314333.4	Gene:	AgaP_AGAP004858 / 1275108	VectorBaseID:	AGAP004858	Length:	435	Species:	Anopheles gambiae

Alignment Length:	223	Identity:	64/223 - (28%)
Similarity:	98/223 - (43%)	Gaps:	38/223 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 CGGTIYRSNQIISAAHCVNTLSG--PE--NLTIVAGSSNIWFPTGP-QQELEVREIIIHPKYRTL 120
            |||::.....:::||||.....|  |:  .|.::..::.::.|... .||..:.....||::...
Mosquito    17 CGGSLITPRHVLTAAHCALNDDGVAPQVVRLGVIDITAGLYDPQNQFAQEYGISSFRRHPEHEFR 81

  Fly   121 NNDYDAAILILDGDFEFNDAVQP--------IELAKERPDHDTPVTVTGWGTTSEGGTISDVLQE 177
            ...:|..::.||......|||.|        :.|.:        :...|:|.||.||..:.:|.:
Mosquito    82 AEYHDIGLVTLDRPVTLTDAVVPACLWTGAQVPLRR--------LEAVGFGQTSFGGERTPILLK 138

  Fly   178 VSVNVVDNSNCKNAYSIM------LTSRMLCAGVNGGGKDACQGDSGGP----LVYNNTLL---- 228
            |.::.||||.|...|...      |..:.:||  :....|.|.||||||    |:.||.|:
Mosquito   139 VQLSPVDNSACGRFYPPSRRRRQGLIDQQMCA--SDERMDTCHGDSGGPLQLKLMANNRLIPFVV 201

  Fly   229 GIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ||.|:|..|.... |.||..|...:|||
Mosquito   202 GITSFGRFCGTAT-PAVYTRVSSYVDWL 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	61/220 (28%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	64/223 (29%)
AgaP_AGAP004858	XP_314333.4	Tryp_SPc	1..229	CDD:238113	64/223 (29%)
		Tryp_SPc	1..227	CDD:214473	61/220 (28%)
		Tryp_SPc	295..>384	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910