DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP005072

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_313947.4	Gene:	AgaP_AGAP005072 / 1274755	VectorBaseID:	AGAP005072	Length:	857	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	77/268 - (28%)
Similarity:	121/268 - (45%)	Gaps:	56/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IPK--LDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV-NTLSG---PENL 87
            :||  |..||..|...:...:|....:.:..:::||.|:.....:::|:||| |:.:|   .|.|
Mosquito    51 VPKIALRSRITDGGVADEGHWPWHGGLFHLNDYQCGCTLINELFVLTASHCVYNSDTGYKISEKL 115

  Fly    88 TIVA---------GSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQP 143
            ..|.         |||.:       |...|::||.|.|:....:.:|.|:|.|:|..:|.:.:||
Mosquito   116 VRVRLGMHRLSANGSSAV-------QTYTVQKIIPHSKFVPNTHKHDVALLRLNGTVKFTNYIQP 173

  Fly   144 I-----------ELAKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNC----KNAYS 193
            :           .||      |...||.|||.| |...|||.|.:..:.:|..::|    .:.|.
Mosquito   174 VCLDLTESIWVEYLA------DVYGTVVGWGLT-EKNRISDQLLKAELPIVRYTDCVESNPDLYG 231

  Fly   194 IMLTSRMLCAGVNGGGKDACQGDSGGPL-VYNNT---LLGIVSW-----GTG-CAREKYPGVYCS 248
            .::.|.|.|||:. .|...|.|||||.: ::...   |.|:||:     ||. |....|. |:.:
Mosquito   232 RLIYSGMYCAGIL-NGTSPCNGDSGGGMYIFRENRWFLRGVVSFSGIREGTNYCDSFSYV-VFMN 294

  Fly   249 VPDVLDWL 256
            ||....|:
Mosquito   295 VPYYAKWI 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	73/257 (28%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	73/259 (28%)
AgaP_AGAP005072	XP_313947.4	Tryp_SPc	59..302	CDD:214473	73/258 (28%)
		Tryp_SPc	60..302	CDD:238113	72/257 (28%)
		IG_like	373..447	CDD:214653
		IGc2	377..436	CDD:197706
		LamG	451..600	CDD:238058
		LamG	673..826	CDD:238058
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910