DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and CLIPB2

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	84/258 - (32%)
Similarity:	125/258 - (48%)	Gaps:	37/258 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYR--GNH---RCGGTIYRSNQIISAAHCVNTLS----------GP 84
            ||:|||.|.:.::|....:.||  ||.   .|||.:..:..|::|||||.:|.          |.
Mosquito   102 RIIGGQTTELEEFPWTALIEYRKPGNQYDFHCGGALINARYILTAAHCVQSLPRGWQLNGVRLGE 166

  Fly    85 ENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDY--DAAILILDGDFEFNDAVQPIELA 147
            .:|:.....|:.....|| .:||:...:.|..|...:..:  |.|::.|..|...::.::||.|.
Mosquito   167 WDLSTANDCSDGICSAGP-IDLEIESFVAHAGYDAADTAHTNDIALIRLRQDVASSEMIRPICLP 230

  Fly   148 KERPDHD-----TPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY---SIMLTSRMLCAG 204
            ...|...     |.....|||.| |..:.|:...:|.:.|.|.|.|:..|   :|.|.:..:||
Mosquito   231 LTEPQRSRNRVGTVSFAAGWGKT-ESASASERKLKVELTVQDPSRCRQIYRGINIALKASQMCA- 293

  Fly   205 VNGG--GKDACQGDSGGPLVYNNT----LLGIVSWG-TGCAREKYPGVYCSVPDVLDWLVETV 260
              ||  |||.|.|||||||:..:.    |:|:||:| :.|....|||||.:|.:.|||:...|
Mosquito   294 --GGLQGKDTCTGDSGGPLMAKSAGAWYLIGVVSFGLSKCGTAGYPGVYTNVVEYLDWIESNV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	81/251 (32%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	82/254 (32%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855
		Tryp_SPc	102..350	CDD:214473	82/252 (33%)
		Tryp_SPc	103..353	CDD:238113	82/254 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910