DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP007280

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_308537.4	Gene:	AgaP_AGAP007280 / 1269883	VectorBaseID:	AGAP007280	Length:	2275	Species:	Anopheles gambiae

Alignment Length:	253	Identity:	87/253 - (34%)
Similarity:	115/253 - (45%)	Gaps:	41/253 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTL--------SGPENLTIVA 91
            |||||...:...||..:.:...|.:.|||:||..:.|||||||.:..        ||.......|
Mosquito   941 RIVGGSHADPEAYPFIVGIFRDGKYHCGGSIYNEHWIISAAHCCDNFDQHYFEVRSGMLRKRSFA 1005

  Fly    92 GSSNIWFPTGPQQEL-EVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPI---ELAKERPD 152
                      ||.:: .|..:|:|..|.:.....|.|::.::..|.:|..|:||   |..:...|
Mosquito  1006 ----------PQVQITRVTHMIVHHAYSSSLMANDIALMRVEHPFHYNRWVRPICMPERHRTTDD 1060

  Fly   153 HD--------TPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGG 209
            .|        |..|..|||...|.|...|.|.:|||.::  ..||:...  ..|..:||....||
Mosquito  1061 RDWIWGPKAGTVCTAIGWGALRERGGAPDHLMQVSVPIL--GYCKHKSD--RDSLQICAAEEDGG 1121

  Fly   210 KDACQGDSGGPLVYNNT-------LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            .||||||||||.|..:.       |.|:||.|.||||...||||..|...:||:.|.|
Mosquito  1122 HDACQGDSGGPFVCQSKSNPFEWYLAGVVSHGEGCARAHEPGVYTRVALFIDWIAEKV 1179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	83/246 (34%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/249 (34%)
AgaP_AGAP007280	XP_308537.4	LDLa	698..733	CDD:238060
		Tryp_SPc	941..1175	CDD:214473	84/247 (34%)
		Tryp_SPc	942..1178	CDD:238113	84/249 (34%)
		LDLa	1196..1226	CDD:238060
		LDLa	1510..1541	CDD:238060
		LDLa	1574..1609	CDD:238060
		DUF1986	1774..1887	CDD:286432
		LDLa	1999..2025	CDD:238060
		LDLa	2038..2071	CDD:238060
		LDLa	2107..2142	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910