DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	273	Identity:	80/273 - (29%)
Similarity:	120/273 - (43%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YRNEEV--HIPKLDGRIVGGQDTNITQYPHQISMRYRG------NHRCGGTIYRSNQIISAAHCV 78
            |.:.|.  .:.|....:.||..|:...:|...::.:||      .:.||.||.....:|:|||||
Mosquito    32 YNDNECGERLVKRQELVKGGYSTHPGDWPWHAALYHRGFNSRDFEYACGSTIVHRYLVITAAHCV 96

  Fly    79 NTLSG-----PENLTIVAGSSNIWFPTGP-QQELEVREIIIHPKYRTLNNDYDAAILILDGDFEF 137
            ...:.     .:|:.:..|..|:...... .:|..|.:.|:|..||....:.|.|||.::....|
Mosquito    97 TFATSRRKIPSDNMQLRLGRFNLMNNEEEYAEEFSVIDTIVHEGYRPTTLENDIAILRVEIPIIF 161

  Fly   138 NDAVQPIELAKERPD-------HDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNC----KNA 191
            ||.:||:.|.| |.|       ::.|.||.||| .||...|...|.|..:.||::..|    :..
Mosquito   162 NDYIQPVCLWK-RDDGFDLPNVYNQPGTVVGWG-LSENNRIGTTLNEAQMPVVNSWTCLASDRAF 224

  Fly   192 YSIMLTSRMLCAGV-NGGGKDACQGDSGGPLVYNNT----LLGIVSWGT------GCAREKYPGV 245
            :...|.|:..|||. ||.|  .|.|||||.:.:...    |.||||:.:      .|...:|.|
Mosquito   225 FGRFLQSKAFCAGYKNGTG--VCNGDSGGGMFFQFQNRWYLKGIVSFSSVNDYSGWCNLRQYIG- 286

  Fly   246 YCSVPDVLDWLVE 258
            :......:||:.|
Mosquito   287 FTDASQYIDWVYE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	74/253 (29%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	77/257 (30%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113	77/255 (30%)
		Tryp_SPc	50..297	CDD:214473	75/251 (30%)
		Tryp_SPc	342..563	CDD:214473
		Tryp_SPc	342..563	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910