DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and f7

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	278	Identity:	98/278 - (35%)
Similarity:	138/278 - (49%)	Gaps:	34/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CSLADPIY--------RNEEV----------------HIPKLDGRIVGGQDTNITQYPHQISMRY 55
            ||.||..|        |:.||                |...|..|||||.:......|.|:.::|
Zfish   151 CSCADGYYLDNGGQKCRSHEVFPCGKVPLLQAGKAADHQVDLRSRIVGGSECPKGHCPWQVLLKY 215

  Fly    56 RGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTL 120
            .....|||.||:...|::||||:..|. .:.|.||||..::....|.:|.::|.::..||.|.:.
Zfish   216 GEKGFCGGVIYKPTWILTAAHCLEKLK-VKFLRIVAGEHDLEVDEGTEQLIQVDQMFTHPAYVSE 279

  Fly   121 NNDYDAAILILDGDFEFNDAVQPI-----ELAKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSV 180
            ..|.|.|:|.|.....::....|:     |:|:......:..||:|||..||.|..|.:|:.:.|
Zfish   280 TADSDIALLRLRTPIVYSVYAVPVCLPLREMAERELWAVSKHTVSGWGKRSEDGPTSRLLRRLLV 344

  Fly   181 NVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPLV--YNNT--LLGIVSWGTGCAREK 241
            ..:....|....::.|||.|.|||...|.:|:|:||||||||  |.:|  ||||||||.||||..
Zfish   345 PRIRTQECVQVSNLTLTSNMFCAGYIEGRQDSCKGDSGGPLVTRYRDTAFLLGIVSWGKGCARPG 409

  Fly   242 YPGVYCSVPDVLDWLVET 259
            ..|:|..|.:.|.|:.:|
Zfish   410 SYGIYTRVSNYLQWIRQT 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	86/228 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/231 (37%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342	5/14 (36%)
		Tryp_SPc	195..424	CDD:214473	86/229 (38%)
		Tryp_SPc	196..427	CDD:238113	86/231 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910