DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and St14

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_446087.1	Gene:	St14 / 114093	RGDID:	69288	Length:	855	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	91/260 - (35%)
Similarity:	135/260 - (51%)	Gaps:	46/260 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRG-NHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSN-IW 97
            |:|||.:.:..::|.|:|:...| .|.||.::...:.::|||||.      ::.||...|.: :|
  Rat   614 RVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCF------QDETIFKYSDHTMW 672

  Fly    98 F-----------PTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERP 151
            .           .....||.:::.||.||.:.....|||.|:|.|:...|::..|:||.|    |
  Rat   673 TAFLGLLDQSKRSASGVQEHKLKRIITHPSFNDFTFDYDIALLELEKPAEYSTVVRPICL----P 733

  Fly   152 D--HDTP----VTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGK 210
            |  |..|    :.|||||.|.||||.:.:||:..:.|::.:.|:......:|.||:|.|...||.
  Rat   734 DNTHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEELLPQQITPRMMCVGFLSGGV 798

  Fly   211 DACQGDSGGPL--------VYNNTLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKESVG 267
            |:|||||||||        ::.   .|:||||.|||:...||||..:|:|.||:      ||..|
  Rat   799 DSCQGDSGGPLSSVEKDGRIFQ---AGVVSWGEGCAQRNKPGVYTRIPEVRDWI------KEQTG 854

Fly 268 267
Rat 855 854

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	86/246 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	87/249 (35%)
St14	NP_446087.1	SEA	88..178	CDD:396113
		CUB	214..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	492..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	88/255 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810