DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and F11

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	259	Identity:	94/259 - (36%)
Similarity:	142/259 - (54%)	Gaps:	23/259 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV 78
            |.||.  :.:.:.|...|::.|:|||..:...::|.|:::.....|.|||:|..:..|::||||.
Mouse   370 GYSLR--LCKMDNVCTTKINPRVVGGAASVHGEWPWQVTLHISQGHLCGGSIIGNQWILTAAHCF 432

  Fly    79 NTLSGPENLTIVAGSSNIWFPTGPQQEL-------EVREIIIHPKYRTLNNDYDAAILILDGDFE 136
            :.:..|:.|.:..|..|       |.|:       .|:|:|||.:|.|..:.||.|:|.|:....
Mouse   433 SGIETPKKLRVYGGIVN-------QSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLESAMN 490

  Fly   137 FNDAVQPIELAK--ERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAY-SIMLTS 198
            :.|..:||.|..  :|....|...|||||.|:..|.:...||:..|.:|.|..|:..| ...:|:
Mouse   491 YTDFQRPICLPSKGDRNAVHTECWVTGWGYTALRGEVQSTLQKAKVPLVSNEECQTRYRRHKITN 555

  Fly   199 RMLCAGVNGGGKDACQGDSGGPL--VYNNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            :|:|||...||||.|:|||||||  .||..  |:||.|||.||.:::.||||.:|...:||::|
Mouse   556 KMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILE 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	86/233 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	88/237 (37%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	3/7 (43%)
		Tryp_SPc	389..617	CDD:214473	87/234 (37%)
		Tryp_SPc	390..617	CDD:238113	86/233 (37%)
		Heparin-binding. /evidence=ECO:0000250	547..550		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810