DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	234	Identity:	85/234 - (36%)
Similarity:	129/234 - (55%)	Gaps:	19/234 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPEN---LTIVAG--SSNI 96
            ||||:::...:|.|.|:.:.....|||::.....::|||||.|   |..|   ||::.|  :.|.
Zfish   309 VGGQNSSAVHWPWQASLYWYSGQTCGGSLINKEWVLSAAHCFN---GQRNGFYLTVILGPKTQNK 370

  Fly    97 WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERP--DHDTPVTV 159
            :.|:  :....|:.:|.||.|....||.|.|::.|.....|.|:::|:.||.|..  :.||...:
Zfish   371 YDPS--RISRSVKAVIKHPYYNPNTNDNDIALVRLSFPITFTDSIRPVCLAAEGSVFNSDTESWI 433

  Fly   160 TGWGTTSEGGTISD--VLQEVSVNVVDNSNCKNAYSI-MLTSRMLCAGVNGGGKDACQGDSGGPL 221
            |.|...|:|..:..  :.|||.|.|:.|..|...|.: .:|..|:|||:...|||.||||||||:
Zfish   434 TTWRNISDGVPLPSPKIFQEVEVPVIGNRQCNCLYGVGSITDNMICAGLLKEGKDLCQGDSGGPM 498

  Fly   222 VYNNTLL----GIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |.|.:.:    ||||:|:|||:.::||||..|....:|:
Zfish   499 VSNQSSVWVQSGIVSFGSGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	84/231 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/234 (36%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035
		Tryp_SPc	309..537	CDD:238113	84/232 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910