DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	92/262 - (35%)
Similarity:	134/262 - (51%)	Gaps:	37/262 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQIS-MRYRGN--HRCGGTIYRSNQIISA 74
            :.|.|:           .|:|.|||||...::..:|.|:. ::..|.  :.|||:|...:.|::|
Frog   253 ISCGLS-----------TKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWIVTA 306

  Fly    75 AHCV-NTLSGPENLTIVAGSSNI--WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFE 136
            |||| .:.|.|....:.|||..|  ::..|    ..|...::||.|.:....||.|:|.|.....
Frog   307 AHCVYGSTSTPSAFKVFAGSLTIQSYYSAG----YTVERALVHPSYSSYTQIYDVALLKLTAALV 367

  Fly   137 FNDAVQPIELAKERPD------HDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA--YS 193
            |...::|:.|    |:      ...|..::|||||:|||:||..|...||.::.::.|..|  |.
Frog   368 FTTNLRPVCL----PNVGMPWAEGQPCWISGWGTTAEGGSISKNLMAASVPIISSTTCNQAAVYG 428

  Fly   194 IMLTSRMLCAGVNGGGKDACQGDSGGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLD 254
            ..::|.|:|||...||.|.||||||||||....    |:|..|||.||||...||||.:|...::
Frog   429 GAISSTMMCAGYLSGGTDTCQGDSGGPLVTKTNSLWWLVGDTSWGYGCARAYKPGVYGNVTVFIE 493

  Fly   255 WL 256
            |:
Frog   494 WI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	87/237 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	87/239 (36%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	2/16 (13%)
		Tryp_SPc	265..498	CDD:238113	87/239 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910