DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	86/238 - (36%)
Similarity:	125/238 - (52%)	Gaps:	20/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 DGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV-NTLSGPENLTIVAGSSNI 96
            :.|||||...:|..:|.|::::|...:.|||::..:|.|::||||| ...|.|.......|  .|
Frog   258 ESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSLWKAFIG--KI 320

  Fly    97 WFPT-GPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDH------D 154
            ..|: .......|..||:||.|.:..|..|.|::.|.....|:...:|:.|    |::      .
Frog   321 KMPSYYDSSAYSVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPVCL----PNYGMQWEEG 381

  Fly   155 TPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDACQGDS 217
            .|..::||||||:.|:||.||:...|.::..:.|...  |:..:||.|:|||...||.|:|||||
Frog   382 QPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDS 446

  Fly   218 GGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |||||....    |:|..|||.|||....||||.::...|.|:
Frog   447 GGPLVTKTNSLWWLVGDTSWGDGCANVYRPGVYGNMTVFLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/233 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/235 (36%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055
		Tryp_SPc	261..489	CDD:238113	84/233 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910