DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and f12

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	88/243 - (36%)
Similarity:	125/243 - (51%)	Gaps:	19/243 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSS 94
            |.:..|||||.......:|: |:..|..||.|||::.....|::||||::.......:::|.|.|
Frog   353 PSIMPRIVGGLVALPASHPY-IAALYIDNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVLGQS 416

  Fly    95 NIWFPTGPQQ--ELEVREIIIHPKYRTLNNDYDAAIL---ILDG--DFEFNDAVQPIELAKE--R 150
            .  |.|..|.  .|.|.:.|:|.||......:|.|::   .::|  ..||:..||||.|.::  .
Frog   417 R--FNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKM 479

  Fly   151 PDHDTPVTVTGWGTTSEGGT-ISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCAGVNGGGKDA 212
            .:......|.|||...||.. .:..|||.|:.::..:.|:  :.:...:...|||||...||.||
Frog   480 AESTKQCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQCQSPSVHGDRMLPGMLCAGFMEGGVDA 544

  Fly   213 CQGDSGGPLVY----NNTLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ||||||||||.    ...|.|:||||:|||.|..||||.:|....||:
Frog   545 CQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWI 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/235 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/237 (36%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	86/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910