DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss3

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	93/252 - (36%)
Similarity:	127/252 - (50%)	Gaps:	18/252 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHC 77
            |.|.|. |.|.:        ..|||||..:.:.|:|.|.|:.::|.|.|||::.....|::||||
Frog   230 VVCGLR-PSYTS--------SARIVGGNVSAVGQWPWQASLVFQGVHLCGGSLITPQWIVTAAHC 285

  Fly    78 VNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQ 142
            |..|..||...:..|..: ......|..:.|::||.|.|||:.....|.|::.|...|.||.::|
Frog   286 VYDLLYPEWWRVQVGQVS-QASESAQTAVPVQKIIYHSKYRSSTMANDIALIRLASPFTFNGSIQ 349

  Fly   143 PIELAKERPD--HDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNC--KNAYSIMLTSRMLCA 203
            ||.|...|.|  ......::|||.|.|||..|..:....|.::.|..|  |..|..::...|:||
Frog   350 PICLPNYREDFPEGKICWISGWGATEEGGDTSQTMDYAGVPLISNRVCNTKYIYGGVIKPSMVCA 414

  Fly   204 GVNGGGKDACQGDSGGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |...||.|.|||||||||...::    |:|..|||.|||....||||..:...|||:
Frog   415 GFLEGGVDTCQGDSGGPLACEDSNVWKLMGTTSWGIGCALRYKPGVYTRISSFLDWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	86/227 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	87/229 (38%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055	3/6 (50%)
		Tryp_SPc	244..472	CDD:238113	87/229 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910