DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss11f

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_004911133.1	Gene:	tmprss11f / 100379970	XenbaseID:	XB-GENE-1012399	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	236	Identity:	81/236 - (34%)
Similarity:	134/236 - (56%)	Gaps:	14/236 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSS 94
            |.:..|||||.:..:..:|.|.|:|..|:|.||.::.....:::||||.:..:...:.|:|.|:.
Frog   191 PSVSNRIVGGTNAGLGSWPWQASLRLLGSHTCGASLLNDTWLVAAAHCFDMNADANSWTVVLGTI 255

  Fly    95 NIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPI---ELAKERPDHDTP 156
            |::  :|  .|.::.:|||:..|.:.|:..|.|:|.|.....|...::|:   |.:...|| .:.
Frog   256 NVY--SG--SEFKIEKIIIYEGYTSHNHRNDIALLKLFTPLNFTSIIRPVCLPEASDIFPD-GSS 315

  Fly   157 VTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDACQGDSGG 219
            ..:||||..::||:.|.|||:..|.::::..|.::  |..::...|:|||...|..|:|||||||
Frog   316 CYITGWGALTDGGSASQVLQQAEVKIINSDTCSSSQMYGGLIYPSMICAGYATGQIDSCQGDSGG 380

  Fly   220 PLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |||...:    |:||||:|.|||....||||..:..:.:|:
Frog   381 PLVTLKSGRWVLIGIVSFGYGCALPNKPGVYSRITYLRNWI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	79/228 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	79/230 (34%)
tmprss11f	XP_004911133.1	SEA	48..148	CDD:396113
tmprss11f	XP_004911133.1	Tryp_SPc	197..421	CDD:238113	78/228 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000