DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss15

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	246	Identity:	89/246 - (36%)
Similarity:	123/246 - (50%)	Gaps:	27/246 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVN----TLSGPENLTIVA 91
            |.:||:|||||.....:|..:|:::.|.|.||.|:.....:|:|||||.    .||   |...|.
Zfish   743 KKEGRVVGGQDAQRGAWPWMVSLQWLGGHACGATLIDREWLITAAHCVYGRNVQLS---NWAAVL 804

  Fly    92 GSSNIWFPTGP-QQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPD--- 152
            |....:....| :|...|.::|:|..|.....:.|.|::.|.....:.|.||||.|    ||
Zfish   805 GLHAQFETINPNKQVFSVDQVIMHKHYNKRTKESDFALMHLKTPVSYTDYVQPICL----PDPGA 865

  Fly   153 ---HDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKN---AYSIMLTSRMLCAGVNGGGKD 211
               ......:.|||..||.|..:||||:..|.::.|:.|:.   .|:  .|.||:|||...||.|
Zfish   866 HFEEGRKCFIAGWGLLSESGLKADVLQQAVVPLLSNTQCQEWLPEYN--FTERMMCAGYAEGGVD 928

  Fly   212 ACQGDSGGPLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            .|||||||||:...    .|:|..|:|.||.|.:.||.|..|...:||:.|
Zfish   929 TCQGDSGGPLMCEEEGHWVLVGATSFGIGCGRPQRPGAYARVSQFVDWVAE 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	84/237 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	86/241 (36%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335
		Tryp_SPc	747..977	CDD:214473	85/238 (36%)
		Tryp_SPc	748..980	CDD:238113	86/241 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810