DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and hpn

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_012811934.1	Gene:	hpn / 100145343	XenbaseID:	XB-GENE-995348	Length:	417	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	99/260 - (38%)
Similarity:	132/260 - (50%)	Gaps:	33/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIV------AGS 93
            |||||||..:.::|.|:|:||.|.|.|||::..|..:::||||.     ||...||      ||:
Frog   162 RIVGGQDATLGRWPWQVSLRYDGAHLCGGSLISSEWVLTAAHCF-----PERNRIVSQWRVFAGA 221

  Fly    94 SNIWFPTGPQQELEVREIIIHPKYRT-LN-----NDYDAAILILDGDFEFNDAVQPI---ELAKE 149
            .:...|.|  :.|.|:.||.|..|.. ||     |..|.|::.|......::.:||:   .|.::
Frog   222 VSQLSPRG--KLLGVKGIIYHSGYLPFLNPDSEENSNDIALVHLASPVTLSEYIQPVCLPALGQQ 284

  Fly   150 RPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDA 212
            ..|... .||:|||.....|..|::|||.||.::.:|.|...  |...:|.:|.|||...||.||
Frog   285 IIDGKI-CTVSGWGNLQYYGQQSEILQEASVPIISSSVCNQPEYYMNQITGKMFCAGYAEGGIDA 348

  Fly   213 CQGDSGGPLVYNNT--------LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKESVGKI 269
            ||||||||.|..:|        |.||||||.|||....||||..|.....|:...:..|..|..|
Frog   349 CQGDSGGPFVCEDTLSRSSRWRLCGIVSWGIGCAMPNKPGVYAKVDQYQYWIYRAMKTKSDVAGI 413

Fly 270 269
Frog 414 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	95/244 (39%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	95/247 (38%)
hpn	XP_012811934.1	Hepsin-SRCR	50..159	CDD:370400
hpn	XP_012811934.1	Tryp_SPc	163..400	CDD:238113	94/244 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000