DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss3a

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	235	Identity:	88/235 - (37%)
Similarity:	125/235 - (53%)	Gaps:	10/235 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSS 94
            ||...|||||..:...|:|.|:|:.::..|.|||:|..|..|::|||||..::.|....:.||.:
Zfish   292 PKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIAYPMYWMVYAGLT 356

  Fly    95 NIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAK--ERPDHDTPV 157
            .:  |....:...|.:||.|.:||....|:|.|::.|.....||..|:||.|..  |:.:.....
Zfish   357 EL--PLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDGKMC 419

  Fly   158 TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCAGVNGGGKDACQGDSGGP 220
            .::|||.|.:||..|......||.::.|..|.  ..|...||:.|:|||...||.|:||||||||
Zfish   420 WISGWGATEDGGDASVSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGP 484

  Fly   221 LVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |...::    |:|..|||.|||.:..||||..:...|.|:
Zfish   485 LACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	85/227 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/229 (37%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	88/235 (37%)
		Tryp_SPc	298..525	CDD:238113	85/229 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810