DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7745 and CG8765

DIOPT Version :9

Sequence 1:	NP_610671.1	Gene:	CG7745 / 36210	FlyBaseID:	FBgn0033616	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_649141.1	Gene:	CG8765 / 40147	FlyBaseID:	FBgn0036900	Length:	690	Species:	Drosophila melanogaster

Alignment Length:	484	Identity:	100/484 - (20%)
Similarity:	147/484 - (30%)	Gaps:	188/484 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DEQLIDEVAQHGVIYNRQKYYLNGGANGGKYETKDEAWQLIAMKLRTDVDTCKKRWKYLRERYVS 67
            :::||..:.|..:|||      .|..|....:.|.|.|:.||.||:..|..|:.:||.||::|..
  Fly   316 EKELITLIQQEDMIYN------YGNENYRNAKLKMEVWEEIARKLKKSVKQCRLKWKALRDQYAR 374

  Fly    68 QRKQGDPPVYEHLSRPYLEKMKFLDQHIQPRKSYRHVPNFLTSPQSANSSGYNEYQVDKSNGSMK 132
            :.|                :::.| .||.....::|               ||.....:.....|
  Fly   375 EHK----------------RLRTL-MHIDATSRWKH---------------YNSLSFLQKYIQQK 407

  Fly   133 NVSQFGSSGQSHLYHQPDQQHAMSALSNVAASALENVNGQVKIEADQVFRDFAAAVASQQLQHIS 197
            .:             :.|.|.:|....|.....||:                          |::
  Fly   408 TL-------------ESDSQLSMLLPKNDPVRELED--------------------------HMT 433

  Fly   198 QSQM--QQQAAAVAAVMADSSQGYQDQYKDGSVGMNGAQNSAGSLTSTSSSMKSPLSSPLQGIGA 260
            ||..  .||                                   :|..|||..|.|:.|......
  Fly   434 QSHSPPTQQ-----------------------------------ITLESSSSNSQLNLPTLPHLT 463

  Fly   261 GSHHPQQQTQQQQQQQQQQAQQQSPASEQQLPVVHSSSSATGASIGNSSTLQMQQSHVYNPKGDG 325
            |.|..:||.|||||::|.|.|||....:|                      |.|.|.:.....|.
  Fly   464 GPHKAEQQQQQQQQEEQHQQQQQHQQQQQ----------------------QQQASELCVATYDD 506

  Fly   326 LDSSSSSHFHMKKPRIQLNGNAHNQMTSNGSHFGNDSDDESDENSHDLME-----PQAMMQQENH 385
            :|..:           .:||:.|:          ||.|.|.||:..  ||     .|...||:.|
  Fly   507 MDIEN-----------YINGDVHH----------NDDDVEDDEDEE--METTTAAEQPPQQQDQH 548

  Fly   386 YSNSMPMQRGNG------NGNNSSSNSGSNNPSGNNSHNNQQQQQHQNMFPSNTDF--------L 436
            .   |.....:|      ....|:.:.......|..|..|||.|       |..:|        .
  Fly   549 V---MTYDHEDGPVYMAVPSVGSAMSKQEQLSDGATSLENQQLQ-------STAEFQKIEIQTPT 603

  Fly   437 FQLYQQFPHQASSSHPANFGKFQAPPNHP 465
            ...||......||:..:.:......|:.|
  Fly   604 TPRYQNAATTPSSTSTSRYHSAPITPSKP 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7745	NP_610671.1	MADF	5..96	CDD:214738	25/90 (28%)
CG8765	NP_649141.1	MADF	42..123	CDD:214738
CG8765	NP_649141.1	MADF	318..405	CDD:214738	29/124 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910