Protein Alignment ING1 and PHO23

DIOPT Version :10

• Sequence 1: NP_005528.4
• Gene: ING1 / 3621
• HGNCID: 6062
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_014302.3
• Gene: PHO23 / 855626
• SGDID: S000005041
• Length: 330
• Species: Saccharomyces cerevisiae
• Alignment Length: 296
• Identity: 70/296 - (23%)
• Similarity: 112/296 - (37%)
• Gaps: 97/296 - (32%)

Human   191 LKELDECYERFSRE---TDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQ---- 248
            :..|:|..::|.::   .|...:.|:|:.:.:.........:||:.:.|.|::.::..|.:
Yeast    43 MPNLNERIDKFLKKDFNKDHQTQVRLLNNINKIYEELMPSLEEKMHVSSIMLDNLDRLTSRLELA 107

Human   249 -----------------VDSH--VELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSR 294
                             ||:|  :.|.....|..::..||           .::||.|..|:|..
Yeast   108 YEVAIKNTEIPRGLRLGVDNHPAMHLHHELMEKIESKSNS-----------KSSQALKSESRREA 161

Human   295 RQRNNENREN-ASSNHDHDDG-----------------ASGTPKEKKAKTS-------KKKKRSK 334
            ...|....|: ::|.|..||.                 .:.|...|:|..:       :.|||.:
Yeast   162 MAANRRQGEHYSASTHQQDDSKNDANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKR 226

Human   335 AKAEREASPADLPI-----------------------------------DPNEPTYCLCNQVSYG 364
            ..|....||:.:..                                   |..||.||.||||:||
Yeast   227 RVATTAVSPSTISTATAVNNGRIGTSTASRGVSSVGNSNNSRISRPKTNDYGEPLYCYCNQVAYG 291

Human   365 EMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 400
            ||:|||..:|.:||||..|:||...|||||||..|:
Yeast   292 EMVGCDGADCELEWFHLPCIGLETLPKGKWYCDDCK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ING1	NP_005528.4	ING_ING1	163..250	CDD:341093	11/82 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..349		23/147 (16%)
		PHD_ING1_2	355..399	CDD:277059	28/43 (65%)
		PBR. /evidence=ECO:0000250|UniProtKB:Q9H160	405..422
PHO23	NP_014302.3	TNG2	5..330	CDD:227367	70/296 (24%)