Protein Alignment Fpps and GGPS1

DIOPT Version :9

• Sequence 1: NP_477380.1
• Gene: Fpps / 36209
• FlyBaseID: FBgn0025373
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001032354.1
• Gene: GGPS1 / 9453
• HGNCID: 4249
• Length: 300
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 77/295 - (26%)
• Similarity: 122/295 - (41%)
• Gaps: 86/295 - (29%)

  Fly   162 EMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMYAI-LKK--HFSHLDCYV 223
            |||.:..::.||:.|||..|||.|..|.:..:. :.||.|    |.:|.: |:|  ...|.|...
Human    54 EMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIP-SVINSA----NYVYFLGLEKVLTLDHPDAVK 113

  Fly   224 ----ALMELFHEITYITTCGQSLD--QLNSNRCVSEFTMENYKAIVENKTAYYSFYLPFALALHL 282
                .|:|| |:       ||.||  ..::..|.:|   |.|||:|..||...     |.||:.|
Human   114 LFTRQLLEL-HQ-------GQGLDIYWRDNYTCPTE---EEYKAMVLQKTGGL-----FGLAVGL 162

  Fly   283 ----AGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGK-IGTDIQDNKCSWLAVVAM- 341
                :.||:     ..|.:|..:|.|||::||:.:.........| ...|:.:.|.|:..:.|:
Human   163 MQLFSDYKE-----DLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIW 222

  Fly   342 -------------QRA-NVEQKQIMVDCYGKEEPAKVERVKELYKELGLPSTYAIFEEESYNMIK 392
                         ||. |::.|:..|  :..|:....|..:...|||         |.::|..|
Human   223 SRPESTQVQNILRQRTENIDIKKYCV--HYLEDVGSFEYTRNTLKEL---------EAKAYKQI- 275

  Fly   393 THIQQTSRG--------VPHQTFLQILNKIYQRDS 419
                 .:||        |.|      |:|:::.::
Human   276 -----DARGGNPELVALVKH------LSKMFKEEN 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fpps	NP_477380.1	polyprenyl_synt	119..377	CDD:278763	68/243 (28%)
GGPS1	NP_001032354.1	polyprenyl_synt	9..251	CDD:395277	63/224 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810