Protein Alignment Fpps and ERG20

DIOPT Version :9

• Sequence 1: NP_477380.1
• Gene: Fpps / 36209
• FlyBaseID: FBgn0025373
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_012368.1
• Gene: ERG20 / 853272
• SGDID: S000003703
• Length: 352
• Species: Saccharomyces cerevisiae
• Alignment Length: 339
• Identity: 147/339 - (43%)
• Similarity: 214/339 - (63%)
• Gaps: 8/339 - (2%)

  Fly    87 FMAVFPDLVRDITTVTKAYNC-SDAAKWFAQVLQYNVPRGKKNRGILTVLTYKNL--VPTQDLTP 148
            |:.|||.||.::.....||.. .:|..|:|..|.||.|.||.|||:..|.||..|  ...:.|..
Yeast    12 FLNVFPKLVEELNASLLAYGMPKEACDWYAHSLNYNTPGGKLNRGLSVVDTYAILSNKTVEQLGQ 76

  Fly   149 ENIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMYAILK 213
            |..:....||||:|:||::|:::||:||.|.||||||||:||..||..|||||.|:|.|:|.:||
Yeast    77 EEYEKVAILGWCIELLQAYFLVADDMMDKSITRRGQPCWYKVPEVGEIAINDAFMLEAAIYKLLK 141

  Fly   214 KHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNR---CVSEFTMENYKAIVENKTAYYSFYLP 275
            .||.:...|:.:.|||||:|:.|..||.:|.:.:..   .:|:|:::.:..||..||||||||||
Yeast   142 SHFRNEKYYIDITELFHEVTFQTELGQLMDLITAPEDKVDLSKFSLKKHSFIVTFKTAYYSFYLP 206

  Fly   276 FALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGKIGTDIQDNKCSWLAVVA 340
            .|||:::||..|.:..:|::.:|:.:|.:||:|||:|||||.||..||||||||||||||:...|
Yeast   207 VALAMYVAGITDEKDLKQARDVLIPLGEYFQIQDDYLDCFGTPEQIGKIGTDIQDNKCSWVINKA 271

  Fly   341 MQRANVEQKQIMVDCYGKEEPAKVERVKELYKELGLPSTYAIFEEESYNMIKTHIQQT--SRGVP 403
            ::.|:.||::.:.:.|||::.....:.|:::.:|.:...|..:||.....:|..|.|.  |||..
Yeast   272 LELASAEQRKTLDENYGKKDSVAEAKCKKIFNDLKIEQLYHEYEESIAKDLKAKISQVDESRGFK 336

  Fly   404 HQTFLQILNKIYQR 417
            .......|||:|:|
Yeast   337 ADVLTAFLNKVYKR 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fpps	NP_477380.1	polyprenyl_synt	119..377	CDD:278763	121/262 (46%)
ERG20	NP_012368.1	polyprenyl_synt	38..305	CDD:395277	123/266 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342122
Domainoid	1	1.000	263	1.000	Domainoid score	I302
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1519
Inparanoid	1	1.050	295	1.000	Inparanoid score	I516
Isobase	1	0.950	-	0	Normalized mean entropy	S785
OMA	1	1.010	-	-		QHG54004
OrthoFinder	1	1.000	-	-		FOG0003736
OrthoInspector	1	1.000	-	-		oto99002
orthoMCL	1	0.900	-	-		OOG6_101661
Panther	1	1.100	-	-	LDO	PTHR11525
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R455
SonicParanoid	1	1.000	-	-		X2592
TreeFam	1	0.960	-	-
	16	15.740