DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fpps and COQ1

DIOPT Version :9

Sequence 1:	NP_477380.1	Gene:	Fpps / 36209	FlyBaseID:	FBgn0025373	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_009557.1	Gene:	COQ1 / 852288	SGDID:	S000000207	Length:	473	Species:	Saccharomyces cerevisiae

Alignment Length:	248	Identity:	56/248 - (22%)
Similarity:	92/248 - (37%)	Gaps:	74/248 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KNRGILTVLTYKNLVPTQDLTPENIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVE 191
            |.||||               |:..:||:    .|||:.:..::.|||:|:|.||||:|..:...
Yeast   167 KQRGIL---------------PKQRRLAE----IVEMIHTASLLHDDVIDHSDTRRGRPSGNAAF 212

  Fly   192 NVGLTAINDALMIENAMYAILKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNRCVSEFTM 256
            ...:..:....::..|..:|.:.|...:   |.||.  :.|..:.. |:.:...|::......|:
Yeast   213 TNKMAVLAGDFLLGRATVSISRLHNPEV---VELMS--NSIANLVE-GEFMQLKNTSIDADIDTI 271

  Fly   257 EN-------------------------------YKAIVENKTAYY--SFYLPFA--------LAL 280
            ||                               :..|:|....||  ..||..|        .|.
Yeast   272 ENGHKLLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRCAA 336

  Fly   281 HLAGYKDA---EAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGK-IGTDIQ 329
            .|:|...|   |.:...:    .:|..||:.||.||...:.:..|| .|.|::
Yeast   337 ILSGASPAVIDECYDFGR----NLGICFQLVDDMLDFTVSGKDLGKPSGADLK 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fpps	NP_477380.1	polyprenyl_synt	119..377	CDD:278763	56/248 (23%)
COQ1	NP_009557.1	Isoprenoid_Biosyn_C1	48..471	CDD:412224	56/248 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810