DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fpps and coq-1

DIOPT Version :9

Sequence 1:	NP_477380.1	Gene:	Fpps / 36209	FlyBaseID:	FBgn0025373	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_491588.1	Gene:	coq-1 / 172190	WormBaseID:	WBGene00000761	Length:	393	Species:	Caenorhabditis elegans

Alignment Length:	442	Identity:	85/442 - (19%)
Similarity:	163/442 - (36%)	Gaps:	102/442 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLPQQRILASPLRLQRLISTSDEVNAEPIIKSMDTIGGLPTELVNEQKLKKTSRTLSTLQNHSVP 72
            :||:..|:|...|...:.:||...::     |.:::..  |..|.|.        :..:||   .
Worm     3 VLPKINIVARQFRKCSMAATSTSTSS-----SDNSVAS--TAFVQEH--------VRQMQN---D 49

  Fly    73 IAARVTVSKDESRDFMAVFPDLVRDITTVTKAYNCSDAAKWFAQ-----------VLQYNVPRGK 126
            |..:: :.:|||        ..|.::..:....|......::.|           :|..|.....
Worm    50 IMVQL-IPQDES--------GAVENLADLNVTSNLGRMTHYYFQQGGKMLRPTVSLLMGNACNSA 105

  Fly   127 KNRGILTVLTYKNLVPTQDLTPENIKLAQYLGWC---------VEMLQSFFIISDDVMDNSTTRR 182
            .||.|..  .|..::.|     |...:|.:|..|         .||:.:..::.|||:|.:.|||
Worm   106 ANRSISE--EYLAMLST-----ERSGIAAHLSVCQNQYKIGMIAEMIHTASLVHDDVIDEANTRR 163

  Fly   183 GQPCWHKVENVGLTAINDALMIENAMYAILKKHFSHLDCYVA---LMELFHEITYITTCGQSLDQ 244
            |....:.|....::.:....::..|         :.:.|.:.   ::.:...|......|:.:..
Worm   164 GSASVNAVWGNKMSVLVGDFILARA---------TQILCSIGKPNIISVMASIIEDLVLGEFMQM 219

  Fly   245 LNSNRCVSEFTMENYKAIVE---NKTAYYSFYLPFALALHLAGYKDAE----AFRQSKTILLEMG 302
              |........::..||.:|   .|||.. |......|..||...|.:    ||...:    .:|
Worm   220 --STTPTDATPVDRMKAYIEKTHRKTASL-FASSCRSAAILADGSDLKLHEIAFEYGR----NLG 277

  Fly   303 NFFQVQDDFLDCFGNPEVTGK-IGTDIQDNKCSWLAVVAMQR---------------ANVEQ-KQ 350
            ..||:.||.||.....:..|| :..|::....:...:.|.::               .:.|: ::
Worm   278 IAFQLADDLLDFIATADEMGKPVAADLKLGLATAPVLYACEQYPELNTMLLRKFKHDGDAEKARE 342

  Fly   351 IMVDCYGKEEPAKVERVKELY--KELGLPSTYAIFEEESYNMIKTHIQQTSR 400
            |:|:..|.:   |..|:.:.|  |.:.:.|:.....|.:.::||..:.|:.|
Worm   343 IVVNSDGMD---KTRRLIDSYSQKAVEMASSLPNRNESTEHLIKLAMSQSDR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fpps	NP_477380.1	polyprenyl_synt	119..377	CDD:278763	58/295 (20%)
coq-1	NP_491588.1	polyprenyl_synt	80..344	CDD:278763	53/286 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810