Protein Alignment Fpps and Fdps

DIOPT Version :9

• Sequence 1: NP_477380.1
• Gene: Fpps / 36209
• FlyBaseID: FBgn0025373
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001240680.1
• Gene: Fdps / 110196
• MGIID: 104888
• Length: 420
• Species: Mus musculus
• Alignment Length: 339
• Identity: 152/339 - (44%)
• Similarity: 228/339 - (67%)
• Gaps: 4/339 - (1%)

  Fly    83 ESRDFMAVFPDLVRDITTVTKAY-NCSDAAKWFAQVLQYNVPRGKKNRGILTVLTYKNLVPTQDL 146
            |.::|:..|..:|:.:|.....: ...||.....:||:||...||.|||:..|..::.||..:..
Mouse    80 EKQNFIQHFSQIVKVLTEKELGHPEIGDAIARLKEVLEYNALGGKYNRGLTVVQAFQELVEPKKQ 144

  Fly   147 TPENIKLAQYLGWCVEMLQSFFIISDDVMDNSTTRRGQPCWHKVENVGLTAINDALMIENAMYAI 211
            ..|:::.|..:|||||:||:||::|||:||:|.|||||.||::...:||.||||||::|.::|.:
Mouse   145 DAESLQRALTVGWCVELLQAFFLVSDDIMDSSLTRRGQICWYQKPGIGLDAINDALLLEASIYRL 209

  Fly   212 LKKHFSHLDCYVALMELFHEITYITTCGQSLDQLNSNR---CVSEFTMENYKAIVENKTAYYSFY 273
            ||.:......|:.|:|||.:.:|.|..||:||.:.:.:   .:..:|.:.||:||:.|||:||||
Mouse   210 LKFYCREQPYYLNLLELFLQSSYQTEIGQTLDLMTAPQGHVDLGRYTEKRYKSIVKYKTAFYSFY 274

  Fly   274 LPFALALHLAGYKDAEAFRQSKTILLEMGNFFQVQDDFLDCFGNPEVTGKIGTDIQDNKCSWLAV 338
            ||.|.|:::||....:....:..||:|||.|||||||:||.||:|.||||:||||||||||||.|
Mouse   275 LPIAAAMYMAGIDGEKEHANALKILMEMGEFFQVQDDYLDLFGDPSVTGKVGTDIQDNKCSWLVV 339

  Fly   339 VAMQRANVEQKQIMVDCYGKEEPAKVERVKELYKELGLPSTYAIFEEESYNMIKTHIQQTSRGVP 403
            ..:.||:.:|:||:.:.||:::|.||.|||.||:.|.|.|.:..:||:|||.:|:.|:|.|..:|
Mouse   340 QCLLRASPQQRQILEENYGQKDPEKVARVKALYEALDLQSAFFKYEEDSYNRLKSLIEQCSAPLP 404

  Fly   404 HQTFLQILNKIYQR 417
            ...|:::.||||:|
Mouse   405 PSIFMELANKIYKR 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fpps	NP_477380.1	polyprenyl_synt	119..377	CDD:278763	125/260 (48%)
Fdps	NP_001240680.1	MSP1_C	72..>144	CDD:284802	19/63 (30%)
		polyprenyl_synt	117..378	CDD:278763	125/260 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833743
Domainoid	1	1.000	261	1.000	Domainoid score	I1953
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1519
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2633
Isobase	1	0.950	-	0	Normalized mean entropy	S785
OMA	1	1.010	-	-		QHG54004
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003736
OrthoInspector	1	1.000	-	-		oto92032
orthoMCL	1	0.900	-	-		OOG6_101661
Panther	1	1.100	-	-	LDO	PTHR11525
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R455
SonicParanoid	1	1.000	-	-		X2592
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740